Analyzing brain blood vessels to understand brain function and diseases
Official title: CRCNS: TopoVess: A Topology-Infomred Vasculature Analysis Platform for Neuroscience
Funded at State University New York Stony Brook · NIH-11162871 · Data updated 2026-11-12
This study is looking at how the blood vessels in the brain work and how they might be linked to conditions like Alzheimer's, stroke, and autism, using special imaging techniques to create a 3D model of mouse brains to help us understand these issues better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project start | December 5, 2024 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $373,778 |
| NIH project number | 1R01NS143143-01 |
| Project ID | NIH-11162871 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals affected by neurodegenerative diseases, vascular conditions, or autism spectrum disorders.
✕Less likely to help
Patients with conditions unrelated to brain vasculature or those not experiencing neurological symptoms may not benefit from this research.
What this research studies
This research focuses on understanding the brain's blood vessels and their role in brain function and various diseases. By utilizing advanced imaging techniques, the project aims to create a detailed 3D model of mouse brain vasculature. The researchers will develop computational algorithms to analyze this vasculature, which is crucial for understanding conditions like Alzheimer's disease, stroke, and autism. This work could lead to better insights into how blood flow affects brain activity and health.
Why it matters
Potential benefit: If successful, this research could improve our understanding of brain diseases and lead to better diagnostic and treatment strategies.
How similar studies have gone: Previous research has shown promise in using advanced imaging and computational analysis for understanding brain function, indicating that this approach could yield valuable insights.
Where this research is happening
-
State University New York Stony Brook
Stony Brook, United States Active
Researchers
- Principal investigator: Chen, Chao — State University New York Stony Brook
- Study coordinator: Chen, Chao
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.