Analyzing biomarkers to predict Alzheimer's disease onset and quality of life.
Integrative analysis for patient-centered outcomes and time-to-event data in Alzheimer's disease
This study is looking for ways to spot early signs of Alzheimer's disease by analyzing genetic information and health records, so we can better understand who might be at risk and how to help them live well before any symptoms show up.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10634872 on NIH RePORTER |
What this research studies
This research aims to develop advanced analytical methods to identify individual biomarker patterns that are linked to the onset of Alzheimer's disease, even before symptoms appear. By examining genetic factors and utilizing extensive electronic health records, the project seeks to create dynamic predictions of disease risk while considering the impact on patients' quality of life. The approach focuses on overcoming current limitations in understanding how biomarkers change over time and their relationship with disease progression. This could lead to more personalized management strategies for individuals at risk of Alzheimer's.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are at risk for Alzheimer's disease, particularly those in the asymptomatic stage.
Not a fit: Patients who are already diagnosed with advanced Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management of Alzheimer's disease, improving patients' quality of life.
How similar studies have performed: Previous research has shown promise in using biomarker analysis for Alzheimer's, but this project aims to introduce novel methodologies that have not been extensively tested.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Zhao, Yize — Yale University
- Study coordinator: Zhao, Yize
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.