Analyzing antibodies using advanced mass spectrometry techniques
Official title: High Mass MALDI TOF Employing a Novel High-Tc Superconducting Ion Detector
Funded at Zeteo Tech, INC. · NIH-10822274 · Data updated 2026-11-12
This study is exploring a new way to better detect and understand antibodies and immune complexes, which could lead to improved tests and treatments for patients with health conditions.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Zeteo Tech, INC. NIH-funded |
| Lab location | 1 site (Sykesville, United States) |
| Project start | September 30, 2024 |
| Project end | September 29, 2025 |
| Funding year | 2024 |
| Award (this year) | $271,495 |
| NIH project number | 1R43GM153742-01 |
| Project ID | NIH-10822274 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with autoimmune diseases or conditions that involve antibody interactions.
✕Less likely to help
Patients who do not have immune-related conditions or who are not affected by antibody-related issues may not benefit from this research.
What this research studies
This research focuses on improving the analysis of antibodies and immune complexes through a novel mass spectrometry technique. By utilizing matrix-assisted laser desorption ionization (MALDI) combined with a high-temperature superconducting ion detector, the study aims to enhance the detection of high mass ions. This approach allows for a clearer understanding of binding interactions and the composition of these biological molecules, which is crucial for various health applications. Patients may benefit from advancements in diagnostics and therapeutics stemming from this improved analytical capability.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostics and targeted therapies for patients with immune-related conditions.
How similar studies have gone: While the use of mass spectrometry in biological analysis is established, the specific combination of MALDI with high-temperature superconducting detection is a novel approach that has not been widely tested.
Where this research is happening
-
Zeteo Tech, INC.
Sykesville, United States Active
Researchers
- Principal investigator: Berkout, Vadym D — Zeteo Tech, INC.
- Study coordinator: Berkout, Vadym D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.