Analyzing 3D heart images to improve understanding of heart function

Secondary Analysis of 3D Echo Images of the Right Ventricle to Compute 3D Surface Strain

NIH-funded research University of Colorado Denver · NIH-11040903

This study is looking at a new way to check how well the right side of the heart is working in people with pulmonary arterial hypertension by using advanced 3D heart images, which could help catch problems earlier and give better information about their heart health.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-11040903 on NIH RePORTER

What this research studies

This research focuses on improving the assessment of right ventricular function in patients with pulmonary arterial hypertension (PAH) by utilizing advanced three-dimensional echocardiography. By analyzing 3D images of the heart, the study aims to compute 3D surface strain values that provide a more comprehensive view of heart contractions compared to traditional 2D methods. This approach could lead to earlier detection of heart dysfunction and better prognostic information for patients. The research will involve secondary analysis of existing echocardiographic data to validate the effectiveness of this new methodology.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with pulmonary arterial hypertension who undergo echocardiographic evaluations.

Not a fit: Patients without pulmonary arterial hypertension or those who do not undergo echocardiographic assessments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic techniques for heart dysfunction, potentially enhancing patient outcomes in those with pulmonary arterial hypertension.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for cardiac assessment, suggesting that this approach could yield significant insights.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.