Anabolic vs. Catabolic Skeletal Effects of Endurance or Resistance Exercise in Older Veterans
Official title: Anabolic Versus Catabolic Skeletal Effects of Endurance or Resistance Exercise in Older Veterans
Funded at VA Eastern Colorado Health Care System · NIH-11317008 · Data updated 2026-11-12
This study will look at how endurance or resistance exercise affects bone health in older veterans and whether exercise improves bone formation or increases bone breakdown.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Eastern Colorado Health Care System NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | April 1, 2022 |
| Project end | March 31, 2027 |
| Funding year | 2027 |
| NIH project number | 5IK2RX003820-05 |
| Project ID | NIH-11317008 on NIH RePORTER |
Who could benefit from this research
✓Could help
Veterans aged 60-80 years who are able to participate in endurance or resistance exercise.
✕Less likely to help
Adults outside the 60-80 year age range or those unable to engage in the specified exercise types may derive less benefit.
What this research studies
In this study, older veterans will participate in structured endurance or resistance exercise to see how their bones respond over time. The researchers will measure changes in calcium balance, hormones, and bone turnover markers after different exercise types and training periods. The goal is to understand whether repeated exercise bouts promote bone formation or bone loss in older adults and how these responses differ between men and women. The findings could guide safe, effective exercise prescriptions to protect bone health in aging veterans.
Why it matters
Potential benefit: If successful, the study could inform exercise guidelines that help older adults build or protect bone mass and reduce fracture risk.
How similar studies have gone: Prior work has shown acute calcium and bone turnover changes with single exercise bouts; this study extends knowledge to training effects and bone formation markers over time.
Where this research is happening
-
VA Eastern Colorado Health Care System
Aurora, United States Active
Researchers
- Principal investigator: Wherry, Sarah J — VA Eastern Colorado Health Care System
- Study coordinator: Wherry, Sarah J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.