An internet program to help prevent and reduce depression in pregnant and postpartum women

A multisite randomized controlled trial of an internet-based program for preventing and reducing perinatal depressive symptoms

NIH-funded research Virginia Commonwealth University · NIH-10810691

This study is testing a friendly online program called 'Mamma Mia' that helps pregnant and new moms manage feelings of sadness, making it easier for them to feel supported and in control during this special time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University NIH-funded
Lab location1 site (Richmond, United States)
Project IDNIH-10810691 on NIH RePORTER

What this research studies

This research investigates an internet-based self-management program called 'Mamma Mia' aimed at preventing and reducing depressive symptoms in pregnant and postpartum women. The program is designed to be easily accessible and cost-effective, allowing women to engage with it during pregnancy and up to six months postpartum. It focuses on enhancing self-efficacy, emotional self-regulation, and perceived social support through a combination of innovative components. The study will evaluate the effectiveness of this program in a large-scale randomized controlled trial across diverse populations in the U.S.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant women or those who have recently given birth and are experiencing depressive symptoms.

Not a fit: Patients who are not pregnant or postpartum, or those who do not experience depressive symptoms, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide pregnant and postpartum women with effective tools to manage and reduce depressive symptoms, improving their mental health and overall well-being.

How similar studies have performed: Previous research in Norway has shown the feasibility and efficacy of the 'Mamma Mia' program, indicating potential for success in the U.S. adaptation.

Where this research is happening

Richmond, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.