An interactive tool to help families communicate hereditary cancer risks.

Development of Family1st-An interactive web-based tool with evidence-based approaches to communicate hereditary cancer risk to at risk relatives and promote cascade testing.

NIH-funded research Beckman Research Institute/city of Hope · NIH-10508426

This study is creating a friendly online tool to help people talk about hereditary cancer risks with their family members, making it easier for patients to share their genetic test results and for relatives to understand their own risks and get the care they need.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionBeckman Research Institute/city of Hope NIH-funded
Lab location1 site (Duarte, United States)
Project IDNIH-10508426 on NIH RePORTER

What this research studies

This research aims to develop an interactive web-based tool that enhances communication about hereditary cancer risks among family members. By integrating communication science and behavioral theory, the project will create a multi-level e-health intervention that encourages patients to share genetic test results with their relatives. The tool will be tested with patients, family members, and healthcare providers to ensure it meets the needs of diverse cultural backgrounds and improves access to genetic testing. Ultimately, the goal is to promote cascade testing, allowing at-risk relatives to understand their own cancer risks and seek appropriate care.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults who have undergone genetic testing for cancer and have family members who may also be at risk.

Not a fit: Patients who do not have a family history of hereditary cancers or who are not interested in genetic testing may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve early detection and treatment options for hereditary cancers among families.

How similar studies have performed: Previous studies have shown that improving communication about genetic risks can enhance family engagement in genetic testing, indicating a promising approach.

Where this research is happening

Duarte, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.