An innovative approach to improve heart health through adaptive interventions.

Learn-As-you-GO (LAGO): An innovative adaptive design for multi-component intervention studies in cardiology and public health

NIH-funded research Yale University · NIH-11036289

This study is looking at how to better prevent and treat heart disease by using a team approach that includes nurses helping with care, managing medications, monitoring blood pressure at home, and using technology to support your health, all tailored to fit your individual needs.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11036289 on NIH RePORTER

What this research studies

This research focuses on enhancing cardiovascular disease prevention and treatment by using complex, multi-component interventions. It involves a combination of nurse-led care coordination, medication management, home blood pressure monitoring, and electronic health record support tools. The study aims to adapt these interventions over time to maximize their effectiveness and cost-efficiency, ensuring that patients receive tailored care based on their specific needs and circumstances. By continuously adjusting the intervention components, the research seeks to improve adherence and overall health outcomes for patients with cardiovascular conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at risk for or currently managing cardiovascular diseases, particularly those needing assistance with blood pressure control.

Not a fit: Patients with stable cardiovascular health and no need for intervention may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized strategies for managing cardiovascular health, ultimately improving patient outcomes.

How similar studies have performed: Previous research has shown promise with similar adaptive intervention approaches in improving health outcomes, indicating potential for success in this novel application.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions cardiac disease prevention
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.