An innovative approach to improve heart health through adaptive interventions.
Official title: Learn-As-you-GO (LAGO): An innovative adaptive design for multi-component intervention studies in cardiology and public health
Funded at Yale University · NIH-11036289 · Data updated 2026-11-12
This study is looking at how to better prevent and treat heart disease by using a team approach that includes nurses helping with care, managing medications, monitoring blood pressure at home, and using technology to support your health, all tailored to fit your individual needs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | February 15, 2024 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $540,265 |
| NIH project number | 5R01HL167936-02 |
| Project ID | NIH-11036289 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for or currently managing cardiovascular diseases, particularly those needing assistance with blood pressure control.
✕Less likely to help
Patients with stable cardiovascular health and no need for intervention may not benefit from this research.
What this research studies
This research focuses on enhancing cardiovascular disease prevention and treatment by using complex, multi-component interventions. It involves a combination of nurse-led care coordination, medication management, home blood pressure monitoring, and electronic health record support tools. The study aims to adapt these interventions over time to maximize their effectiveness and cost-efficiency, ensuring that patients receive tailored care based on their specific needs and circumstances. By continuously adjusting the intervention components, the research seeks to improve adherence and overall health outcomes for patients with cardiovascular conditions.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized strategies for managing cardiovascular health, ultimately improving patient outcomes.
How similar studies have gone: Previous research has shown promise with similar adaptive intervention approaches in improving health outcomes, indicating potential for success in this novel application.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Spiegelman, Donna L — Yale University
- Study coordinator: Spiegelman, Donna L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.