An injectable electrode for treating high blood pressure and heart failure
Official title: The Injectrode- An injectable, easily removable electrode as a trial lead for baroreceptor activation therapy to treat hypertension and heart failure
Funded at Neuronoff, INC. · NIH-10697600 · Data updated 2026-11-12
This study is testing a new, easy-to-remove injectable device that helps control high blood pressure and heart failure by stimulating a specific area in your neck, offering a gentler option than traditional surgery, and it's for people looking for better ways to manage these conditions.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Neuronoff, INC. NIH-funded |
| Lab location | 1 site (Valencia, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $596,582 |
| NIH project number | 1R43HL169127-01 |
| Project ID | NIH-10697600 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who have hypertension resistant to standard treatments or are suffering from heart failure.
✕Less likely to help
Patients with mild hypertension or those who respond well to standard pharmacological treatments may not benefit from this research.
What this research studies
This research investigates a new injectable electrode designed to activate the baroreflex, which can help manage hypertension and heart failure. The electrode is easily removable and aims to provide a less invasive alternative to traditional surgical methods. By stimulating the carotid sinus bulb, the therapy seeks to induce significant changes in blood pressure regulation. Patients will be monitored to assess the effectiveness of this approach compared to existing treatments.
Why it matters
Potential benefit: If successful, this research could offer a less invasive treatment option for patients with resistant hypertension and heart failure.
How similar studies have gone: Previous studies have shown success with baroreflex activation therapy, indicating potential for this novel approach.
Where this research is happening
-
Neuronoff, INC.
Valencia, United States Active
Researchers
- Principal investigator: Franke, Manfred — Neuronoff, INC.
- Study coordinator: Franke, Manfred
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.