NIH-funded research Sbir 1 grant

An app that uses AI to help detect eye misalignment in children and adults.

Official title: iLIGN - Artificial Intelligence Driven Strabismus Pre-Screening System

Funded at Ther-Ai LLC · NIH-10921579 · Data updated 2026-11-12

This study is testing a new smartphone app called iLIGN that helps anyone easily check for strabismus, a condition where the eyes aren't aligned, so that people can get early help and avoid future vision problems.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionTher-Ai LLC
NIH-funded
Lab location1 site (Kissimmee, UNITED STATES)
Project startSeptember 1, 2024
Project endAugust 31, 2025
Funding year2024
Award (this year)$295,766
NIH project number1R43EY035599-01A1
Project IDNIH-10921579 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include children and adults who may exhibit signs of strabismus or have a family history of the condition.

Less likely to help

Patients who do not have strabismus or related ocular misalignment issues may not benefit from this research.

What this research studies

This research aims to create a smartphone application called iLIGN that utilizes artificial intelligence to quickly and accurately screen for strabismus, a condition where the eyes are not properly aligned. The app is designed to be user-friendly, allowing individuals without specialized training to perform the screening. By making this technology accessible, the goal is to facilitate early diagnosis and treatment of strabismus, which can prevent long-term vision problems and improve quality of life. The app will be non-invasive and cost-effective, making it suitable for widespread use.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection and treatment of strabismus, reducing the risk of permanent vision loss and improving overall visual health.

How similar studies have gone: Previous research has shown that AI-driven diagnostic tools can effectively improve screening processes in various medical fields, suggesting a promising potential for this approach in strabismus detection.

Where this research is happening

  • Ther-Ai LLC
    Kissimmee, United States
    Active

Researchers

  • Principal investigator: Shaikh, Saad — Ther-Ai LLC
  • Study coordinator: Shaikh, Saad

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.