Alzheimer’s genetics in African and Hispanic communities
Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
Collecting genetic and health information from people of African and Hispanic ancestry to learn how genes influence Alzheimer’s disease risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11380209 on NIH RePORTER |
What this research studies
You would be invited to join a large effort focused on people of African and Hispanic ancestry to help improve understanding of Alzheimer’s genetics. The team plans to enroll about 13,000 participants, collect health and cognitive information, and ask for a DNA sample using community-sensitive recruitment approaches to build trust. Your sample will be genotyped and combined with other data to find genetic differences that affect Alzheimer’s risk in diverse groups. The goal is to make genetic findings and future care fairer and more accurate for underrepresented communities.
Who could benefit from this research
Good fit: Adults of African, African American, African Caribbean, or Hispanic/Latino ancestry, with or without Alzheimer’s disease, who are willing to provide health information and a DNA sample are the ideal candidates.
Not a fit: People who are not of the targeted ancestries, minors, or those unwilling to provide a DNA sample or basic health information are unlikely to be eligible or to benefit directly from participation.
Why it matters
Potential benefit: If successful, the work could improve risk prediction, diagnosis, and future treatments for Alzheimer’s disease in people of African and Hispanic ancestry.
How similar studies have performed: Earlier genetic studies in European ancestry groups have identified important risk genes, and smaller studies in African American groups have found different risk signals but were underpowered, so this larger, diverse effort expands on proven methods at greater scale.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.