Alzheimer's clinical trials network
Alzheimer's Clinical Trials Consortium (ACTC)
A national effort that runs and improves clinical trials to find better treatments and tests for people with Alzheimer’s disease and related dementias.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11177625 on NIH RePORTER |
What this research studies
This project maintains and expands a nationwide network of Alzheimer’s trial sites led by teams at USC, Harvard, Mayo Clinic, and 35 expert centers. The consortium streamlines contracting and uses a centralized IRB, modern informatics, and advanced statistics to make trials run more efficiently. It tests and embeds new outcome tools like Tau PET imaging and computerized cognitive tests and builds a platform for quick proof-of-concept trials. The program also mentors and brings on new sites to increase patient access to trials.
Who could benefit from this research
Good fit: People with Alzheimer’s disease or related cognitive impairment — from early memory problems to established dementia — who are willing and eligible to join clinical trials at participating sites.
Not a fit: People without Alzheimer’s or related cognitive conditions, or those who cannot travel to or meet eligibility criteria for participating trial sites, are unlikely to benefit directly.
Why it matters
Potential benefit: Could speed up testing of treatments and improve access and measurement tools so effective therapies are found and delivered sooner.
How similar studies have performed: This continues an existing ACTC that has already run Alzheimer’s clinical trials and contributed to advances in trial design and biomarker use, though many treatments studied remain investigational.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Aisen, Paul S. — University of Southern California
- Study coordinator: Aisen, Paul S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.