Allergy data and analysis hub
Data Integration and Analysis Core
This project brings together medical, genetic, and lab data to help researchers understand why children develop, keep, or outgrow allergies like asthma, eczema, and food allergies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-11103183 on NIH RePORTER |
What this research studies
This hub collects clinical records, allergy test results, and biological data from children with asthma, eczema, allergic rhinitis, food allergy, or EoE and combines them into a shared database. Experts use genetics, genomics, statistics, and bioinformatics to look for patterns in how the skin and airway lining (epithelia) drive allergic inflammation. The core links clinical, lab, and population studies across the Center so findings from different projects can be analyzed together. That combined approach is meant to reveal why some kids' allergies persist while others improve or resolve.
Who could benefit from this research
Good fit: Children (about 0–11 years old) with asthma, atopic dermatitis, allergic rhinitis, food allergy, or eosinophilic esophagitis, and their families willing to share health records or samples, are the ideal participants for related studies.
Not a fit: Adults without these allergic conditions or people unwilling to share medical or genetic data are unlikely to benefit directly from this center's work.
Why it matters
Potential benefit: If successful, the work could help predict which children will have persistent allergy and point to new targets to prevent or stop allergic progression.
How similar studies have performed: Previous funding cycles from this Center have produced findings implicating epithelial pathways, but integrating multi-site clinical and multi-omic data in this coordinated way is still relatively new.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Martin, Lisa J — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Martin, Lisa J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.