Alcohol, metabolism, and heart health in people with HIV
Official title: Alcohol and Metabolic Dysregulation in PWH: Mechanisms Underlying Risk for Comorbidities
Funded at Lsu Health Sciences Center · NIH-11416375 · Data updated 2026-11-12
This grant explores how alcohol use worsens metabolic health in people living with HIV and aims to find ways to restore energy production in cells to reduce heart and metabolic problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lsu Health Sciences Center NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project start | December 1, 1996 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $98,061 |
| NIH project number | 5P60AA009803-33 |
| Project ID | NIH-11416375 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with HIV who consume alcohol and are at risk for cardiometabolic issues may be eligible.
✕Less likely to help
People without HIV or those who do not consume alcohol may not directly benefit from these findings.
What this research studies
People with HIV often drink alcohol. This project looks at how alcohol affects metabolism and cellular energy in this population, drawing on long-term study data and primate models. It seeks to test interventions that boost mitochondrial energy production to improve metabolic balance and lower cardiometabolic risk. The work integrates clinical observations with preclinical findings to identify targets for reducing disease risk in PWH.
Why it matters
Potential benefit: If successful, it could lead to strategies that protect metabolic health and reduce heart and aging risks for people living with HIV who use alcohol.
How similar studies have gone: Previous CARC data and NOAH studies hint that metabolic and gut-related changes are modifiable, supporting potential benefit from this approach.
Where this research is happening
-
Lsu Health Sciences Center
New Orleans, United States Active
Researchers
- Principal investigator: Molina, Patricia E. — Lsu Health Sciences Center
- Study coordinator: Molina, Patricia E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.