NIH-funded research Sbir 1 grant

AI tool to identify heart risks from chest CT scans

Official title: AutoChamber: an FDA-Designated Breakthrough AI Add-on to Coronary Artery Calcium and Lung Cancer Screening CT Scans to Flag Patients at High Risk of Atrial Fibrillation, Stroke and Heart Failure

Funded at Heartlung Corporation · NIH-10922647 · Data updated 2026-11-12

This study is testing a new AI tool called AutoChamber that looks at chest CT scans to find early signs of heart problems, helping to spot patients who might be at risk for issues like atrial fibrillation or stroke, all without needing any special dyes.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionHeartlung Corporation
NIH-funded
Lab location1 site (Torrance, United States)
Project startSeptember 27, 2024
Project endSeptember 26, 2025
Funding year2024
Award (this year)$294,023
NIH project number1R43HL174376-01
Project IDNIH-10922647 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who have undergone chest CT scans for various medical evaluations, particularly those at risk for cardiovascular diseases.

Less likely to help

Patients who have not had a chest CT scan or those with pre-existing severe heart conditions may not benefit from this research.

What this research studies

This research develops an AI tool called AutoChamber that analyzes chest CT scans to detect signs of heart conditions, such as enlarged cardiac chambers and thickened heart walls, without the need for contrast agents. By screening existing scans used for other medical evaluations, the tool aims to identify patients at high risk for atrial fibrillation, stroke, and heart failure. This innovative approach leverages the vast number of CT scans already performed to improve early detection and prevention of serious cardiovascular issues.

Why it matters

Potential benefit: If successful, this research could lead to earlier identification and management of heart conditions, potentially saving lives and reducing healthcare costs.

How similar studies have gone: Other research has shown promise in using AI for medical imaging, indicating that this approach could be effective in improving cardiovascular risk assessment.

Where this research is happening

  • Heartlung Corporation
    Torrance, United States
    Active

Researchers

  • Principal investigator: Naghavi, Morteza — Heartlung Corporation
  • Study coordinator: Naghavi, Morteza

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.