NIH-funded research R01 grant

AI tool to detect retinopathy of prematurity in preterm infants

Official title: Deep Learning-based Diagnosis of Retinopathy of Prematurity

Funded at The Trustees of the Stevens Institute of Technology · NIH-11164687 · Data updated 2026-11-12

Using artificial intelligence to help doctors spot sight-threatening retinopathy in premature babies.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionThe Trustees of the Stevens Institute of Technology
NIH-funded
Lab location1 site (Hoboken, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2028
Funding year2025
Award (this year)$504,847
NIH project number5R01EY036203-02
Project IDNIH-11164687 on NIH RePORTER

Who could benefit from this research

Could help

Premature infants undergoing ROP screening whose retinal images can be shared with the research team with parental consent.

Less likely to help

Adults, children without ROP, or infants who do not have retinal imaging available would not directly participate or benefit from this project.

What this research studies

As a parent of a premature infant, this project aims to create an AI that learns from retinal photos to recognize treatment-needed ROP such as plus disease. The team will expand limited training data using image-augmentation techniques and work to make images from different cameras comparable. They will train and test the model to improve consistent detection despite variable image quality. The goal is a reliable diagnostic aid that can be applied across hospitals and imaging systems.

Why it matters

Potential benefit: Could enable earlier and more consistent detection of treatment-required ROP, helping reduce preventable childhood blindness.

How similar studies have gone: AI has successfully aided detection of other retinal diseases and some early ROP tools showed promise, but applying models across different cameras and small infant datasets remains a challenge.

Where this research is happening

  • The Trustees of the Stevens Institute of Technology
    Hoboken, United States
    Active

Researchers

  • Principal investigator: Kang-Mieler, Jennifer J — The Trustees of the Stevens Institute of Technology
  • Study coordinator: Kang-Mieler, Jennifer J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.