AI prediction of one-year death and repeat stroke after ischemic stroke
Machine Learning Prediction of 1-Year Mortality and Recurrence after Ischemic Stroke Using Enriched EHR data
['FUNDING_R01'] · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · NIH-11144923
This project uses artificial intelligence and medical record data to predict whether people who had an ischemic stroke will die or have another stroke within one year.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PENNSYLVANIA STATE UNIV HERSHEY MED CTR (nih funded) |
| Locations | 1 site (HERSHEY, UNITED STATES) |
| Trial ID | NIH-11144923 on ClinicalTrials.gov |
What this research studies
If you've had an ischemic stroke, researchers will use electronic health records from multiple hospitals to train AI models that estimate your chance of dying or having another stroke within 12 months. They will enrich those records with extra clinical details and compare different machine-learning methods to find the most accurate predictions. The team will test the models across different health systems to reduce bias and improve how well the predictions work for many people. The idea is to make a reliable tool clinicians could use to spot patients at higher risk and guide follow-up care.
Who could benefit from this research
Good fit: People who have experienced an ischemic stroke and whose electronic health records are available in the participating hospitals would be the ideal candidates for the underlying data used in this work.
Not a fit: People without accessible electronic health records in the participating systems, those with hemorrhagic (non-ischemic) strokes, or patients with very incomplete medical records may not benefit from these predictions.
Why it matters
Potential benefit: If successful, this could help clinicians identify stroke survivors at high risk and target prevention and follow-up care to reduce deaths and recurrent strokes.
How similar studies have performed: Earlier pilot models using EHR data and machine learning showed promising accuracy but were limited to a single health system and need broader validation.
Where this research is happening
HERSHEY, UNITED STATES
- PENNSYLVANIA STATE UNIV HERSHEY MED CTR — HERSHEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ABEDI, VIDA — PENNSYLVANIA STATE UNIV HERSHEY MED CTR
- Study coordinator: ABEDI, VIDA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.