AI-powered brain-healthy tool to help diagnose and guide treatment for opioid use disorder
Official title: Development of an AI-empowered device that utilizes multimodal data-visualization to aid in the diagnosis, and treatment, of OUD
Funded at Wavi Company · NIH-11363282 · Data updated 2026-11-12
A new AI-based device and brain-activity tests will help clinics quickly identify cognitive changes in people with opioid use disorder to tailor treatment.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wavi Company NIH-funded |
| Lab location | 1 site (Englewood, UNITED STATES) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,208,000 |
| NIH project number | 4R44DA058431-02 |
| Project ID | NIH-11363282 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with opioid use disorder enrolling in or undergoing rehabilitation who can complete brief cognitive and brain-assessment testing.
✕Less likely to help
Patients who cannot tolerate brief cognitive testing or have conditions that interfere with brain measurements may not benefit.
What this research studies
This project partners with eight rehab clinics serving about 150 patients per week to collect data and improve a multimodal brain assessment tool called WAVi. The device combines EEG-derived responses with other cognitive and behavioral measures to create a fast, low-cost profile of a patient’s cognitive state. The goal is to link cognitive patterns with rehabilitation outcomes so clinicians can adjust treatment and reduce relapse. The work will develop a scalable product that clinics can use during intake and follow-up to guide care decisions.
Why it matters
Potential benefit: If successful, the tool could help clinicians personalize OUD treatment and reduce relapse and readmission rates.
How similar studies have gone: Previous research suggests that cognitive markers and brain testing can inform addiction treatment, but this project aims to create a practical, scalable solution for real-world clinics.
Where this research is happening
-
Wavi Company
Englewood, United States Active
Researchers
- Principal investigator: Oakley, David — Wavi Company
- Study coordinator: Oakley, David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.