AI heart imaging markers to track heart aging and stress

Artificial Intelligence Imaging Biomarkers of Longitudinal Cardiovascular Stress

NIH-funded research Kaiser Foundation Research Institute · NIH-11247509

Using artificial intelligence on heart images to spot signs of aging and stress that could help adults, especially older adults, learn about their future heart disease risk earlier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKaiser Foundation Research Institute NIH-funded
Lab location1 site (Oakland, UNITED STATES)
Project IDNIH-11247509 on NIH RePORTER

What this research studies

You or people like you would have past and/or future heart images (for example, echocardiograms) and health records used to train AI that looks for subtle changes over time. The team will apply deep learning to large sets of cardiac images from adults, with a focus on how the heart changes as people age. The project aims to create imaging biomarkers that indicate a person’s cardiovascular ‘age gap’ and rising stress before symptoms start. If you participate, your imaging and clinical data could help improve tools that track heart health across years.

Who could benefit from this research

Good fit: Adults aged 21 and older—particularly people 65 and up or those with cardiovascular risk factors—who can provide or obtain heart imaging and related medical records are the ideal candidates.

Not a fit: People without any available heart imaging, children, or those looking for immediate treatment rather than long-term risk information are unlikely to gain direct benefit from this research.

Why it matters

Potential benefit: If successful, this could allow earlier detection of worsening heart health and better targeting of prevention for people at higher cardiovascular risk.

How similar studies have performed: Previous work shows AI can extract age, sex, and risk-factor signals from heart images, but using longitudinal imaging to build validated cardiovascular aging biomarkers is a newer area that still needs confirmation.

Where this research is happening

Oakland, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.