AI-guided personalized care for chronic sinus inflammation
The Chronic Rhinosinusitis (CRS) Problem and an AI Driven Personalized Medicine Solution
['FUNDING_R01'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-11249223
Using AI to personalize treatments for adults with chronic sinus inflammation so people get the therapies most likely to relieve their symptoms.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INDIANA UNIVERSITY INDIANAPOLIS (nih funded) |
| Locations | 1 site (INDIANAPOLIS, UNITED STATES) |
| Trial ID | NIH-11249223 on ClinicalTrials.gov |
What this research studies
You would share your symptoms, medical history, exam findings, and sinus imaging so researchers can build a detailed profile. The team will apply machine learning to find patterns that predict which treatments—like medication changes or surgery—are most likely to help you. That personalized information could be used to guide treatment decisions and track how you respond over time. Participation may include clinic visits, questionnaires, imaging, and sharing relevant health records or samples.
Who could benefit from this research
Good fit: Adults (21+) with ongoing chronic rhinosinusitis who have not had adequate relief from medical therapy or are thinking about surgery.
Not a fit: People under 21, those with a short-term acute sinus infection, or individuals whose symptoms are caused by non-sinus conditions are unlikely to benefit.
Why it matters
Potential benefit: Could help people with chronic sinus problems get the right treatment faster, improve symptoms, and avoid unnecessary procedures.
How similar studies have performed: Prior work using clinical and imaging markers has shown some ability to predict treatment outcomes, but fully AI-driven personalized prediction for CRS remains a newer and developing approach.
Where this research is happening
INDIANAPOLIS, UNITED STATES
- INDIANA UNIVERSITY INDIANAPOLIS — INDIANAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RAMAKRISHNAN, VIJAY — INDIANA UNIVERSITY INDIANAPOLIS
- Study coordinator: RAMAKRISHNAN, VIJAY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.