NIH-funded research U01 cooperative agreement

AI-guided newborn heart ultrasound for congenital heart defect diagnosis in Sub-Saharan Africa

Official title: Artificial Intelligence assisted echocardiography to facilitate optimal image extraction for congenital heart defects diagnosis in Sub-Saharan Africa

Funded at Health Research Foundation · NIH-11167476 · Data updated 2026-11-12

Using AI to help local health workers capture clearer newborn heart ultrasound images so babies in Sub-Saharan Africa get quicker and more accurate diagnoses of congenital heart defects.

More Echocardiography research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionHealth Research Foundation
NIH-funded
Lab location1 site (Buea, CAMEROON)
Project startSeptember 20, 2023
Project endJuly 31, 2026
Funding year2025
Award (this year)$205,407
NIH project number5U01HL172179-03
Project IDNIH-11167476 on NIH RePORTER

Who could benefit from this research

Could help

Newborns (0–4 weeks old) born at or screened in participating hospitals or clinics in Sub-Saharan Africa, especially those with abnormal pulse oximetry or signs of heart problems.

Less likely to help

Older children, adults, infants outside participating sites, or babies with conditions not detectable by echocardiography are unlikely to benefit directly.

What this research studies

If your baby is born at a participating hospital, this project uses AI software to guide health workers to take the right ultrasound pictures of the heart. The AI helps extract the best images from scans and highlights findings that may indicate a congenital heart defect for remote expert review. This approach aims to reduce long, risky trips to distant pediatric cardiology centers and speed up confirmation after an abnormal pulse oximetry screen. The AI tool is designed to complement training so improvements persist despite staff turnover.

Why it matters

Potential benefit: Faster, more accurate newborn heart diagnoses closer to home, which could reduce dangerous travel and delays in treatment.

How similar studies have gone: Training programs and some AI-assisted echocardiography efforts have improved image capture and remote diagnosis elsewhere, but applying AI for newborn CHD detection in Sub-Saharan Africa is a relatively new application.

Where this research is happening

  • Health Research Foundation
    Buea, Cameroon
    Active

Researchers

  • Principal investigator: Leke, Aminkeng Zawuo — Health Research Foundation
  • Study coordinator: Leke, Aminkeng Zawuo

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.