NIH-funded research R01 grant

AI-enhanced lung ultrasound for detecting tuberculosis in low-resource settings

Official title: Lung Ultrasound and Artificial Intelligence Technology for the Diagnosis of TB in LMICs

Funded at Johns Hopkins University · NIH-11506691 · Data updated 2026-11-12

This project uses portable lung ultrasound combined with AI to help detect tuberculosis in adults in low- and middle-income countries.

More Ultrasound research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startFebruary 15, 2024
Project endJanuary 31, 2029
Funding year2026
Award (this year)$103,684
NIH project number3R01HL168261-03S1
Project IDNIH-11506691 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults (21+) with symptoms suggestive of pulmonary TB who present to participating clinics in low- and middle-income countries.

Less likely to help

People under 21, those with only extrapulmonary TB or no respiratory symptoms, or those not seen at participating sites are unlikely to benefit directly from this project.

What this research studies

If you have symptoms that could be tuberculosis, clinicians would use a handheld lung ultrasound device to scan your chest while an AI tool looks for signs of TB in real time. The team plans to refine how scans are done and how much training operators need so the test works well in busy, resource-limited clinics. Early data suggest lung ultrasound finds many cases, and adding AI aims to make readings faster and more consistent across users. The work will be done at clinics in low- and middle-income countries with oversight from a Johns Hopkins research team.

Why it matters

Potential benefit: If successful, this approach could give faster and more accessible TB screening at the point of care, helping people start treatment sooner.

How similar studies have gone: Small preliminary studies showed lung ultrasound can be highly sensitive for pulmonary TB and the AI approach is promising, but large, well-powered trials integrating real-time AI remain limited.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Gilman, Robert H — Johns Hopkins University
  • Study coordinator: Gilman, Robert H

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.