NIH-funded research R01 grant

AI-enhanced echocardiogram to predict heart surgery and heart failure outcomes

Official title: Radiomics approach to engineering an artificial intelligence based echocardiography platform to predict cardiovascular surgery and heart failure outcomes.

Funded at Stanford University · NIH-11252601 · Data updated 2026-11-12

This project builds an AI tool that reads full echocardiogram videos to help predict recovery after heart surgery and future risks for people with heart failure.

More Heart Failure research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startJanuary 1, 2022
Project endDecember 31, 2026
Funding year2026
Award (this year)$541,116
NIH project number5R01HL157235-05
Project IDNIH-11252601 on NIH RePORTER

Who could benefit from this research

Could help

People with heart failure or those being evaluated for, undergoing, or recovering from cardiovascular surgery who have echocardiogram studies would be the most relevant candidates.

Less likely to help

People without heart disease, without echocardiogram images, or whose care does not rely on echo measurements are unlikely to benefit directly.

What this research studies

If I were a patient, researchers would use advanced AI to treat my echocardiogram videos as rich data rather than just simple measurements. They will train the system on many time-resolved echo studies linked to real patient outcomes so the AI can learn which motion and texture patterns matter. The team plans to validate the multi-modal platform by comparing its predictions to actual surgical and heart-failure results. This work is led at Stanford and would use patients' echo images and medical records under privacy protections.

Why it matters

Potential benefit: If successful, the tool could provide earlier and more accurate predictions about who will do well after heart surgery or who faces higher risk from heart failure, helping tailor care.

How similar studies have gone: AI has performed well in many medical imaging tasks and some echo automation exists, but using radiomics on full echo videos to predict surgical and heart-failure outcomes is relatively new.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Hiesinger, William — Stanford University
  • Study coordinator: Hiesinger, William

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.