NIH-funded research NIH-funded research

AI-assisted digital twin for personalized phonosurgery planning

Official title: Development of AI-Assisted digital twin system for phonosurgery

Funded at Rochester Institute of Technology · NIH-11421268 · Data updated 2026-11-12

A new AI-powered digital twin will simulate a patient’s vocal fold biology to help tailor phonosurgery for clearer, more reliable voice restoration.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRochester Institute of Technology
NIH-funded
Lab location1 site (Rochester, United States)
Project startSeptember 1, 2026
Project endAugust 31, 2030
Funding year2026
Award (this year)$145,613
NIH project number1R16DC024029-01A1
Project IDNIH-11421268 on NIH RePORTER

Who could benefit from this research

Could help

Individuals scheduled for phonosurgery or considering phonosurgical intervention who want a personalized planning tool.

Less likely to help

Patients not undergoing phonosurgery or without access to the digital twin workflow may not benefit directly.

What this research studies

This project aims to create a patient-specific, computer-based model of the vocal folds that uses advanced AI and physics-informed techniques to simulate how surgery will affect voice. It will combine clinical data, tissue properties, and high-fidelity simulations to predict outcomes before actual surgery. The team will address uncertainty and provide surgeons with optimization options to improve safety and effectiveness. The goal is to give patients clearer voices with fewer unexpected results through personalized virtual testing.

Why it matters

Potential benefit: If successful, patients could receive more accurate surgical plans that lead to better voice quality and fewer postoperative surprises.

How similar studies have gone: Previous efforts using computational models have faced challenges in accuracy and reliability, making this a novel but promising approach.

Where this research is happening

  • Rochester Institute of Technology
    Rochester, United States
    Active

Researchers

  • Principal investigator: Zheng, Xudong — Rochester Institute of Technology
  • Study coordinator: Zheng, Xudong

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.