Aging, sleep, and memory and physical health in older women with and without breast cancer
Official title: Patterns of biological, cognitive, and physical aging in cancer survivors and controls and the role of sleep health: Relevance for Alzheimer's Disease and Related Dementias
Funded at University of California Los Angeles · NIH-11306080 · Data updated 2026-11-12
This project explores how biological aging and sleep relate to thinking and physical abilities in older breast cancer survivors and similar women without cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | June 15, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2026 |
| Award (this year) | $780,390 |
| NIH project number | 5R01AG082348-04 |
| Project ID | NIH-11306080 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are older women, particularly breast cancer survivors and similar-aged women without cancer, who are willing to have sleep monitored, give blood samples, and complete cognitive and physical tests.
✕Less likely to help
Men, much younger adults, or people with cancers other than breast cancer are unlikely to be directly helped by this specific project.
What this research studies
If you take part, researchers will follow older women who had breast cancer and a comparable group without cancer over time and collect blood samples and health measures. They will monitor sleep patterns, run memory and thinking tests, and measure physical abilities like walking and strength. The team will compare biological aging markers, sleep health, and changes in thinking and physical function between survivors and controls. The goal is to see whether poor sleep or accelerated biological aging links to memory problems and physical decline.
Why it matters
Potential benefit: If successful, this work could point to sleep or aging-related targets to help detect or slow memory and physical decline in older breast cancer survivors.
How similar studies have gone: Previous research links poor sleep and biological aging to cognitive decline, but there are few long-term studies focused on older breast cancer survivors, so this approach is relatively novel for that group.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Carroll, Judith E — University of California Los Angeles
- Study coordinator: Carroll, Judith E
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.