Affordable screening for stroke risk in children with sickle cell disease
Official title: Affordable Shortwave Infrared Spectroscopy for Stroke Risk Screening in Children with Sickle Cell Disease
Funded at Kennesaw State University · NIH-10730967 · Data updated 2026-11-12
This study is looking for a simple and affordable way to check if children with sickle cell disease are at risk for strokes, using a new method that could help catch problems early and keep them safe.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kennesaw State University NIH-funded |
| Lab location | 1 site (Kennesaw, United States) |
| Project start | September 21, 2023 |
| Project end | September 20, 2026 |
| Funding year | 2023 |
| Award (this year) | $426,714 |
| NIH project number | 1R15EB034986-01 |
| Project ID | NIH-10730967 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children with sickle cell disease, particularly those living in low-resource settings where current screening methods are not accessible.
✕Less likely to help
Patients who do not have sickle cell disease or those living in high-resource settings with access to existing screening methods may not benefit from this research.
What this research studies
This research focuses on developing a cost-effective and non-invasive method to screen for stroke risk in children with sickle cell disease (SCD). The current standard screening method, transcranial ultrasound doppler (TCD), is expensive and not widely available in low-resource settings like sub-Saharan Africa. The new approach involves using shortwave infrared spectroscopy to measure cerebral blood flow, which could help identify children at risk for stroke much earlier. By improving access to screening, the research aims to facilitate timely interventions that could prevent strokes in this vulnerable population.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of strokes in children with sickle cell disease by enabling early detection and intervention.
How similar studies have gone: Previous research has shown that innovative screening methods can effectively reduce stroke risk in similar populations, indicating potential success for this novel approach.
Where this research is happening
-
Kennesaw State University
Kennesaw, United States Active
Researchers
- Principal investigator: Lee, Seung Yup — Kennesaw State University
- Study coordinator: Lee, Seung Yup
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.