Affordable same-day HPV screening and treatment in South Africa

Research Project 2

NIH-funded research Columbia University Health Sciences · NIH-11146519

Finding ways to make same-day HPV testing and immediate treatment affordable and available for people getting cervical cancer screening in South Africa.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11146519 on NIH RePORTER

What this research studies

This project focuses on bringing HPV-based same-day screen-and-treat (SAT) into routine public clinics in Khayelitsha, South Africa. Using a WHO costing tool, the team will compare costs of cervical cancer screening before and after introducing the Xpert HPV point-of-care SAT to calculate cost per person screened and cost per person screened and treated. They will perform time-and-motion and other implementation analyses to measure staff time, workflows, and financing needs for scaling the approach. The project builds on long-term collaboration between Columbia University and the University of Cape Town and uses linked implementation work to tailor affordable, scalable strategies.

Who could benefit from this research

Good fit: People with cervixes who seek cervical cancer screening at public primary care clinics in Khayelitsha, South Africa are the ideal candidates to take part or benefit.

Not a fit: People who do not attend the targeted clinics, who live outside the implementation area, or who are not seeking screening are unlikely to be directly helped by this project.

Why it matters

Potential benefit: If successful, this could lower the cost and increase uptake of same-day HPV screening and treatment in public clinics, helping prevent more cervical cancer deaths.

How similar studies have performed: Point-of-care HPV tests such as Xpert have shown promise and cost-effectiveness in research settings, but broad real-world roll-out of screen-and-treat is still limited.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer CauseCancer ControlCancer Control ScienceCancer EtiologyCancers
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.