Advancing new therapies to close the survivorship gap for pediatric and young adult lymphoma
Official title: Advancing novel therapeutics and translational science to close the survivorship gap in pediatric, adolescent and young adult (AYA) lymphoma
Funded at Emory University · NIH-11411250 · Data updated 2026-11-12
A cancer research grant aims to speed up safer, targeted treatments for Hodgkin lymphoma in kids and young adults to improve survival and long-term health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | August 9, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $178,909 |
| NIH project number | 5R50CA285492-03 |
| Project ID | NIH-11411250 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children, adolescents, and young adults with Hodgkin lymphoma who may participate in immunotherapy or CD30-targeted therapy trials.
✕Less likely to help
Patients without access to trial sites or who have disease not responsive to the investigational approaches may not benefit.
What this research studies
This project focuses on bringing newer therapies like antibody-drug conjugates and immunotherapies into treatment for Hodgkin lymphoma in patients aged 0 to 29. It plans collaborative trials across national networks to test initial and relapse therapies while reducing long-term treatment-related harm. The work will also study tumor biology and how patient factors influence response to tailor treatment plans. National data efforts and post-treatment follow-up will help connect trial results with real-world outcomes. At the local level, the program will implement quality initiatives to improve patient enrollment in trials at Emory and affiliated centers.
Why it matters
Potential benefit: If successful, patients could receive more effective, less harmful treatments with better long-term health and survival.
How similar studies have gone: Previous trials in HL with novel therapies show promise, but integrating these approaches into AYAs and standard care is still evolving.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Castellino, Sharon Marie — Emory University
- Study coordinator: Castellino, Sharon Marie
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Understanding how survivorship care plans affect health outcomes for cancer survivors
A study will look at whether survivorship care plans help reduce deaths and improve health for adults who have survived cancer.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.