Advancing Care for Critically Ill Children
Official title: Collaborative Pediatric Critical Care Research Network - Clinical Site
Funded at University of Colorado Denver · NIH-11180302 · Data updated 2026-11-12
This network helps develop and test new treatments for children who are seriously ill or injured.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | August 18, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $126,000 |
| NIH project number | 5RL1HD107775-05 |
| Project ID | NIH-11180302 on NIH RePORTER |
Who could benefit from this research
✓Could help
This network focuses on children aged 0-11 years old who are critically ill or injured, particularly those with acute lung or kidney issues.
✕Less likely to help
Patients who are not critically ill or are outside the pediatric age range would not directly benefit from this specific research.
What this research studies
Our team at the University of Colorado Denver and Children's Hospital Colorado is part of a larger group dedicated to finding better ways to care for children who are critically ill or injured. We work together with other hospitals to conduct important clinical trials, which are special studies that test new treatments and approaches. Our specific strengths include understanding heart and lung conditions in children and successfully running these types of studies. The aim is to quickly bring new scientific discoveries from the lab directly to the bedside to help young patients.
Why it matters
Potential benefit: If successful, this work could lead to more effective treatments and improved outcomes for children facing life-threatening illnesses and injuries.
How similar studies have gone: This network has a strong history of successful collaboration and has already contributed to important discoveries in pediatric critical care.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Maddux, Aline Bernard — University of Colorado Denver
- Study coordinator: Maddux, Aline Bernard
Related research
Other NIH-funded projects on the same topics.
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Collaborative Pediatric Critical Care Clinical Site (CPCCRN)
A nationwide network is testing personalized care approaches for seriously ill children with sepsis to improve outcomes.
-
Collaborative Pediatric Critical Care Research Network: personalized care for septic kids
A nationwide network is testing personalized treatment approaches for children with sepsis-related organ failure to improve outcomes.
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Collaborative Pediatric Critical Care Network Site: Kids’ Sepsis Care
A pediatric-focused NIH grant supports a network site that helps tailor sepsis care for critically ill children across multiple centers.
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Personalized care for septic children through immunomodulation in MODS
This project tests a custom approach to treating pediatric sepsis in kids with organ failure by tailoring treatments to each child’s immune profile.
-
Personalized immune-based care for septic kids with organ failure
A network study helps critically ill children with sepsis who have organ failure by tailoring treatments to their individual immune profiles.
-
Collaborative Pediatric Critical Care Clinical Site for Precision Sepsis Care
A pediatric-focused research grant exploring personalized care for kids with severe sepsis to improve outcomes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.