Advanced Whole-Body MRI for Finding and Tracking Bone Lesions
Next-Generation Whole-Body MRI for Detection and Assessment of Therapy Response in Bone Lesions
This project develops a new type of whole-body MRI to better find bone lesions from cancers and other conditions, and to see how well treatments are working.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11171692 on NIH RePORTER |
What this research studies
Bone lesions, which can come from cancers like breast, prostate, or kidney cancer, or from conditions like multiple myeloma, can cause significant pain and serious complications. Current methods for finding these lesions often only detect them at advanced stages. This project is creating a new MRI technique called DETECT that aims to improve how clearly these lesions appear on scans, making them easier to spot. The goal is to provide a more comfortable and faster scanning experience while offering clearer images, which could help doctors make better decisions about your care.
Who could benefit from this research
Good fit: Ideal candidates for future applications of this technology would be patients with solid tumors, multiple myeloma, or other musculoskeletal conditions that cause bone lesions.
Not a fit: Patients without bone lesions or those not undergoing imaging for such conditions would not directly benefit from this specific imaging technology.
Why it matters
Potential benefit: If successful, this new MRI technique could lead to earlier detection of bone lesions and more accurate monitoring of how well treatments are working, potentially improving patient outcomes and quality of life.
How similar studies have performed: The novel DETECT technique has shown promising initial results in increasing lesion detection and reducing scan times compared to existing whole-body MRI methods.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Madhuranthakam, Ananth J — Mayo Clinic Rochester
- Study coordinator: Madhuranthakam, Ananth J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.