Advanced tools to understand brain connections and health
Community-supported open-source software for computational neuroanatomy
This project creates advanced computer tools to better understand how brain connections work and how they relate to brain health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trustees of Indiana University NIH-funded |
| Lab location | 1 site (Bloomington, United States) |
| Project ID | NIH-11145088 on NIH RePORTER |
What this research studies
Our brains have complex networks that connect different regions, and these connections are important for how we think, feel, and behave. This project develops new computer methods and software to analyze special MRI scans called diffusion MRI (dMRI), which can show these brain connections without surgery. By improving these tools, we can get a clearer picture of how brain networks function and how they might be affected in various brain conditions. This work helps researchers better understand the brain and could lead to new ways to help people with neurological, cognitive, and psychiatric health challenges.
Who could benefit from this research
Good fit: This foundational work does not directly involve patient participation, but future clinical applications of these tools could benefit individuals with neurological, cognitive, or psychiatric conditions.
Not a fit: Patients not affected by neurological, cognitive, or psychiatric conditions may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of brain disorders and potentially improve diagnosis and treatment strategies for neurological, cognitive, and psychiatric conditions.
How similar studies have performed: Diffusion MRI (dMRI) is already used in research and clinical settings, and this project builds upon and advances existing methods for analyzing this type of brain imaging data.
Where this research is happening
Bloomington, United States
- Trustees of Indiana University — Bloomington, United States (Active)
Researchers
- Principal investigator: Garyfallidis, Eleftherios — Trustees of Indiana University
- Study coordinator: Garyfallidis, Eleftherios
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.