Advanced spinal cord stimulation for treating chronic pain without opioids
Official title: High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic Pain
Funded at Micro-Leads, INC. · NIH-10782012 · Data updated 2026-11-12
This study is testing a new type of spinal cord stimulation called HD64, designed to help people with chronic nerve pain feel better and rely less on pain medications like opioids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Micro-Leads, INC. NIH-funded |
| Lab location | 1 site (Somerville, UNITED STATES) |
| Project start | September 30, 2019 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $640,917 |
| NIH project number | 5U44NS115111-05 |
| Project ID | NIH-10782012 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic neuropathic pain, particularly those who have not found relief through conventional treatments or are dependent on opioids.
✕Less likely to help
Patients with acute pain conditions or those who do not have neuropathic pain may not benefit from this research.
What this research studies
This research focuses on developing a new spinal cord stimulation therapy called HD64, which uses a high-resolution, 64-channel system to target chronic neuropathic pain more effectively. The approach aims to provide pain relief with greater specificity, potentially reducing reliance on opioids for those suffering from debilitating pain in the trunk and extremities. By utilizing ultra-thin and conformal leads, the therapy seeks to stimulate specific nerve fibers while minimizing risks associated with traditional methods. Patients may experience improved quality of life and reduced pain through this innovative treatment.
Why it matters
Potential benefit: If successful, this research could significantly reduce chronic pain and opioid dependence for millions of patients.
How similar studies have gone: Previous research has shown that spinal cord stimulation can effectively relieve chronic pain, indicating a promising potential for this novel approach.
Where this research is happening
-
Micro-Leads, INC.
Somerville, United States Active
Researchers
- Principal investigator: Mclaughlin, Bryan L — Micro-Leads, INC.
- Study coordinator: Mclaughlin, Bryan L
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.