Advanced protein and metabolic testing for stomach (gastric) cancer
Proteomics and Metabolomics
This project uses high‑precision protein and metabolite measurements to help researchers learn how gastric cancer tissues change at the molecular level.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11307043 on NIH RePORTER |
What this research studies
From the patient perspective, researchers use state‑of‑the‑art mass spectrometers and tissue imaging to measure proteins, modified proteins, lipids, metabolites, and iron in stomach cancer samples. The Core processes samples, runs multidimensional LC‑MS/MS and data‑independent acquisition, and creates high‑resolution molecular images linked to pathology. Work includes studies of rodent models and ex vivo human tissue samples, and core staff provide experimental design consultation and hands‑on sample preparation and data analysis. These services support multiple investigators working on gastric cancer within the program.
Who could benefit from this research
Good fit: Patients with gastric cancer who can provide biopsy or surgical tissue samples (or who are treated at centers collaborating with Vanderbilt) would be the most relevant contributors.
Not a fit: People without stomach (gastric) disease or patients who cannot provide tissue samples are unlikely to directly benefit from this core's activities.
Why it matters
Potential benefit: If successful, this work could reveal molecular markers or pathways that enable earlier detection or new treatment targets for gastric cancer.
How similar studies have performed: Proteomics and metabolomics approaches have identified useful biomarkers in other cancers, so this is a promising but still exploratory approach for gastric cancer.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Schey, Kevin L — Vanderbilt University Medical Center
- Study coordinator: Schey, Kevin L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.