Advanced NMR technology for studying biomolecules
Official title: 700MHZ NMR spectrometer with cryogenically cooled probe
Funded at University of Pittsburgh at Pittsburgh · NIH-10851136 · Data updated 2026-11-12
This study is all about getting a super advanced NMR machine that helps scientists better understand the tiny building blocks of life, like proteins and other biomolecules, which can lead to exciting new discoveries in health and medicine.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | May 15, 2024 |
| Project end | May 14, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,211,143 |
| NIH project number | 1S10OD036236-01 |
| Project ID | NIH-10851136 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals involved in studies of biomolecular interactions and those with conditions related to the biological systems being analyzed.
✕Less likely to help
Patients with conditions unrelated to biomolecular research or those not participating in related studies may not receive direct benefits from this research.
What this research studies
This research focuses on acquiring a state-of-the-art 700 MHz NMR spectrometer with a cryogenically cooled probe to enhance the study of biomolecules. The new equipment will allow researchers to obtain high-quality, high-sensitivity spectra from both purified biomolecules in solution and labeled biomolecules within living cells. By replacing outdated technology, this project aims to support cutting-edge biomedical research and improve the capabilities for structural and dynamic analysis of various biological systems. This advancement will facilitate ongoing NIH-funded projects and enable new research opportunities.
Why it matters
Potential benefit: If successful, this research could significantly improve the understanding of biomolecular structures and dynamics, leading to advancements in biomedical applications.
How similar studies have gone: Previous research utilizing advanced NMR technology has shown significant success in enhancing our understanding of biomolecular interactions, indicating that this approach is well-supported by existing evidence.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Hinck, Andrew P — University of Pittsburgh at Pittsburgh
- Study coordinator: Hinck, Andrew P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.