Advanced MRI technology to study infectious diseases in small animals
7T Cryogen-Free Preclinical MRI for small animals to study infectious diseases in BSL-3 containment
This study is working on a new type of MRI machine to help scientists see how serious infections, like tuberculosis and drug-resistant bacteria, develop in a safe lab setting, so they can find better ways to diagnose and treat these diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10415250 on NIH RePORTER |
What this research studies
This research focuses on developing a state-of-the-art 7T Cryogen-Free preclinical MRI system to investigate infectious diseases in a controlled laboratory environment. By utilizing advanced imaging techniques, the project aims to visualize and monitor the progression of diseases caused by highly virulent pathogens, such as Mycobacterium tuberculosis and multi-drug resistant bacteria. The goal is to enhance our understanding of disease mechanisms and support the development of new diagnostics and treatments. This research will be conducted at a specialized facility that meets strict biosafety requirements for handling dangerous pathogens.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals affected by infectious diseases, particularly those caused by multi-drug resistant pathogens.
Not a fit: Patients with non-infectious diseases or those not affected by the specific pathogens being studied may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostics and treatments for infectious diseases, ultimately enhancing patient care.
How similar studies have performed: Previous research has shown success with advanced imaging techniques in studying infectious diseases, indicating a promising approach for this project.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Jain, Sanjay — Johns Hopkins University
- Study coordinator: Jain, Sanjay
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.