Advanced MRI technology for studying brain microstructure
Official title: High Performance Gradient System for Advanced Microstructure MRI - Resubmission - 1
Funded at New York University School of Medicine · NIH-10869642 · Data updated 2026-11-12
This study is exploring a new way to use MRI scans to get a clearer picture of the tiny structures in the brain, which could help us learn more about how the brain develops, ages, and how it’s affected by neurological disorders, ultimately aiming to improve diagnosis and understanding for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $2,000,000 |
| NIH project number | 1S10OD034309-01A1 |
| Project ID | NIH-10869642 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with neurological disorders or those undergoing evaluation for brain-related conditions.
✕Less likely to help
Patients with conditions unrelated to neurological disorders or those who do not require advanced imaging may not benefit from this research.
What this research studies
This research focuses on enhancing MRI technology to noninvasively investigate the microstructure of the brain, which is crucial for understanding human development, aging, and neurological disorders. By utilizing a state-of-the-art MRI scanner with significantly stronger magnetic field gradients, researchers aim to improve the accuracy of imaging vital cellular properties such as axon diameters and myelin thickness. The project involves advanced biophysical modeling of MRI signals to extract detailed information from the brain's microstructure. Patients may benefit from improved diagnostic capabilities and better understanding of neurological conditions through this innovative imaging approach.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and treatment plans for patients with neurological disorders.
How similar studies have gone: Previous research has shown promising results with advanced MRI techniques, indicating potential for significant advancements in brain imaging.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Fieremans, Els — New York University School of Medicine
- Study coordinator: Fieremans, Els
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.