Advanced mass-spectrometry for studying proteins and metabolism
TimsTOF-fleX MALDI-2 mass-spectrometer
This study is looking at how proteins and other substances in the body affect brain health and diseases like neurodegeneration, with the hope that what we learn could help develop new treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Advanced Science Research Center NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10853995 on NIH RePORTER |
What this research studies
This research involves the acquisition of a state-of-the-art mass-spectrometer that will enable detailed studies of proteins and metabolites in various biological contexts. By utilizing advanced trapped-ion mobility technology, researchers will investigate the dynamics of proteins involved in critical biological processes, such as cell signaling and tumor progression. The research aims to enhance our understanding of how metabolic signals influence brain health and disease, particularly in relation to neurodegeneration and glial cell function. Patients may benefit from insights gained through this research that could lead to new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with metabolic disorders, neurodegenerative diseases, or conditions affecting glial cells.
Not a fit: Patients with unrelated conditions or those not affected by metabolic or protein-related disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating diseases related to metabolism and protein function.
How similar studies have performed: Other research utilizing advanced mass-spectrometry techniques has shown promising results in understanding complex biological processes, indicating that this approach is likely to yield valuable insights.
Where this research is happening
New York, United States
- Advanced Science Research Center — New York, United States (Active)
Researchers
- Principal investigator: Abzalimov, Rinat — Advanced Science Research Center
- Study coordinator: Abzalimov, Rinat
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.