Advanced Imaging to Understand Cancer Cells
Highly multiplexed tissue imaging with high-plex in situ signal amplification
This project is developing a new imaging method to see many different molecules in cancer cells and tissues at the same time, helping us learn more about cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard University NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11075844 on NIH RePORTER |
What this research studies
Cancer cells have unique features, like specific proteins and RNA, that are important for understanding their behavior. This project is building an advanced imaging system to map these features within cancer tissues with high detail. By seeing many different molecules at once, we hope to get a clearer picture of various cancer cell types and their surroundings. This new tool aims to overcome limitations of current methods, offering higher detail and sensitivity for both proteins and RNA.
Who could benefit from this research
Good fit: This foundational research does not involve direct patient participation, but future studies using this technology could benefit patients with various types of cancer.
Not a fit: Patients seeking immediate treatment options would not directly benefit from this early-stage technology development.
Why it matters
Potential benefit: If successful, this new imaging platform could provide researchers with a powerful tool to better understand cancer, potentially leading to new ways to diagnose or treat the disease.
How similar studies have performed: While other imaging methods exist, this project aims to develop a novel platform that offers higher multiplexing and sensitivity for co-imaging proteins and RNA in whole tissues.
Where this research is happening
Cambridge, United States
- Harvard University — Cambridge, United States (Active)
Researchers
- Principal investigator: Yin, Peng — Harvard University
- Study coordinator: Yin, Peng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.