Advanced imaging technology for studying tissues at The Ohio State University
Official title: Bruker timsTOF fleX MALDI-2 for Biomedical Research at The Ohio State University
Funded at Ohio State University · NIH-11102145 · Data updated 2026-11-12
This study is all about using a new, advanced tool to take super detailed pictures of tissues at the tiny, single-cell level, which will help researchers learn more about diseases by spotting important small molecules like amino acids and fatty acids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | April 15, 2025 |
| Project end | April 14, 2026 |
| Funding year | 2025 |
| Award (this year) | $750,000 |
| NIH project number | 1S10OD036284-01A1 |
| Project ID | NIH-11102145 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions that affect tissue composition or function, such as metabolic disorders or cancers.
✕Less likely to help
Patients with conditions that do not involve significant tissue analysis or those not located near the research facility may not receive direct benefits from this research.
What this research studies
This research focuses on acquiring a state-of-the-art mass spectrometer that enhances tissue imaging capabilities for biomedical research. The Bruker timsTOF fleX MALDI-2 instrument allows for high-resolution imaging at the single-cell level and improves the detection of small molecules like amino acids and fatty acids. By utilizing advanced techniques such as post-ionization and trapped ion mobility, this technology aims to provide detailed insights into the biochemical landscape of tissues, which can lead to better understanding of various diseases.
Why it matters
Potential benefit: If successful, this research could significantly improve the ability to analyze and understand complex biological tissues, leading to advancements in disease diagnosis and treatment.
How similar studies have gone: Other research has shown success with similar advanced imaging technologies, indicating a promising potential for breakthroughs in biomedical research.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Hummon, Amanda B. — Ohio State University
- Study coordinator: Hummon, Amanda B.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.