Advanced imaging technology for detailed examination of retinal cells
Full Field OCT for Cellular Level Structural and Functional Retinal Imaging
This study is working on a new imaging system that can quickly take detailed pictures of the tiny cells in your retina, helping us understand how they respond to light, especially for people with early-stage age-related macular degeneration.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10677655 on NIH RePORTER |
What this research studies
This research focuses on developing a new optical coherence tomography (OCT) system that can rapidly capture structural and functional images of individual retinal cells, specifically cone and rod photoreceptors. By utilizing a full-field swept-source OCT approach, the study aims to measure neuronal responses to light stimuli with high speed and resolution. The project involves designing the OCT system, testing it on both human and mouse models, and assessing its ability to detect changes in retinal health, particularly in patients with early-stage age-related macular degeneration.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with early-stage age-related macular degeneration as well as healthy volunteers for comparison.
Not a fit: Patients with advanced retinal diseases or those who do not have any retinal conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic capabilities for retinal diseases, allowing for earlier detection and better management of conditions like age-related macular degeneration.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for retinal analysis, indicating that this approach could yield significant insights.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Doble, Nathan — Ohio State University
- Study coordinator: Doble, Nathan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.