Advanced imaging techniques to understand tendon injuries
Official title: High throughput isotropic resolution fluorescence and second Harmonic imaging to characterize tendon injury
Funded at University of Rochester · NIH-11001227 · Data updated 2026-11-12
This study is looking at new ways to take detailed pictures of the cells around tendon injuries to better understand how they heal, which could help find new treatments for people dealing with tendon problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | December 15, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $460,131 |
| NIH project number | 5R01AR082324-02 |
| Project ID | NIH-11001227 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with tendon injuries or conditions that may lead to tendon adhesions.
✕Less likely to help
Patients with non-tendon related injuries or conditions may not benefit from this research.
What this research studies
This research focuses on developing cutting-edge imaging methods to explore the cellular environment surrounding tendon injuries. By using high-resolution two-photon microscopy, the team aims to visualize and analyze the complex interactions of cells involved in tendon healing. The study utilizes advanced techniques to create a three-dimensional view of tissue, which can provide insights that traditional methods cannot. This innovative approach may lead to a better understanding of tendon adhesions and potential new therapies for patients suffering from tendon injuries.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for tendon injuries, enhancing recovery and reducing complications.
How similar studies have gone: Other research has shown promise using advanced imaging techniques in similar contexts, indicating potential for success in this novel approach.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Giacomelli, Michael Gene — University of Rochester
- Study coordinator: Giacomelli, Michael Gene
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.