Advanced imaging techniques for studying proteins in cells and tissues
Super-multiplexed fluorescence nanoscopy for imaging-based proteomics
This study is testing a new imaging technique that helps scientists see more than twenty different proteins in cells and tissues quickly, which could lead to better understanding of diseases like cancer and neurological disorders, ultimately helping patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Central Florida NIH-funded |
| Lab location | 1 site (Orlando, United States) |
| Project ID | NIH-10914160 on NIH RePORTER |
What this research studies
This research focuses on developing a novel imaging technique called super-multiplexed immunofluorescence nanoscopy, which allows for the visualization of over twenty different proteins in cells and tissues within a single day. By utilizing advanced methods such as DNA-barcoded secondary nanobodies and fast stimulated emission depletion microscopy, the research aims to overcome current limitations in protein imaging, including time consumption and resolution issues. Patients may benefit from this research as it could lead to a better understanding of disease mechanisms, particularly in cancers and neurological disorders, through improved protein interaction mapping.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cancers or neurological disorders who may benefit from advanced diagnostic techniques.
Not a fit: Patients with conditions unrelated to protein interactions or those not requiring advanced imaging techniques may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance our understanding of disease mechanisms and lead to more effective treatments for various conditions.
How similar studies have performed: Other research has shown success with advanced imaging techniques, indicating a promising potential for breakthroughs in understanding complex diseases.
Where this research is happening
Orlando, United States
- University of Central Florida — Orlando, United States (Active)
Researchers
- Principal investigator: Han, Kyu Young — University of Central Florida
- Study coordinator: Han, Kyu Young
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.