Advanced imaging techniques for RNA and protein in tissues
Hybridization Chain Reaction: Automated Ultrasensitive Multiplex RNA and Protein Imaging
This study is working on a new way to take detailed pictures of RNA and proteins in tissues, which could help doctors better understand diseases and how patients respond to treatments, making it easier to diagnose and manage health conditions.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Molecular Instruments, INC. NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10822977 on NIH RePORTER |
What this research studies
This research focuses on developing a new method for imaging RNA and proteins in biological tissues with high sensitivity and the ability to analyze multiple targets simultaneously. By utilizing advanced techniques like hybridization chain reaction, the project aims to overcome current limitations in existing imaging methods, which often struggle with sensitivity and multiplexing capabilities. Patients may benefit from improved diagnostic tools that provide better insights into disease mechanisms and treatment responses. The research will involve automated imaging processes that can analyze large areas of tissue quickly and accurately.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that require detailed analysis of RNA and protein expression in tissues, such as cancer or other complex diseases.
Not a fit: Patients with conditions that do not involve significant RNA or protein expression analysis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostics and personalized treatment strategies for various diseases.
How similar studies have performed: Previous research has shown promise in similar imaging techniques, indicating potential for success in this novel approach.
Where this research is happening
Los Angeles, United States
- Molecular Instruments, INC. — Los Angeles, United States (Active)
Researchers
- Principal investigator: Choi, Harry Ming Tak — Molecular Instruments, INC.
- Study coordinator: Choi, Harry Ming Tak
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.