Advanced imaging techniques for observing multiple molecules in live cells
Super-Multiplexed Molecular Sensing in Live Cells
['FUNDING_R01'] · EMORY UNIVERSITY · NIH-11223084
This study is working on new ways to take pictures of different molecules inside living cells all at once, which could help us better understand how cells behave and improve treatments for patients with various conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11223084 on ClinicalTrials.gov |
What this research studies
This research focuses on developing innovative imaging methods to visualize many different molecules within live cells simultaneously. By overcoming limitations of traditional fluorescence microscopy, the project aims to create new vibrational probes that can detect various cellular analytes, including reactive species and metal ions, in real-time. The approach utilizes advanced techniques like Stimulated Raman Scattering (SRS) to provide detailed insights into dynamic biological processes. Patients may benefit from improved understanding of cellular behaviors related to their conditions through enhanced imaging capabilities.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with conditions that involve complex cellular dynamics, such as cancer or metabolic disorders.
Not a fit: Patients with stable, non-dynamic conditions may not receive significant benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding cellular processes, potentially improving diagnosis and treatment strategies for various diseases.
How similar studies have performed: While the use of advanced imaging techniques like SRS is gaining traction, this specific approach to super-multiplexed sensing in live cells is relatively novel and has not been extensively tested.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BUCCELLA, DANIELA — EMORY UNIVERSITY
- Study coordinator: BUCCELLA, DANIELA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.