Advanced imaging techniques for observing cell behavior in tissues
Official title: Concurrent volumetric imaging with multimodal optical systems
Funded at Trustees of Indiana University · NIH-10877767 · Data updated 2026-11-12
This study is testing a new way to take detailed pictures of cells in their natural environment to help researchers understand how tissues heal and respond to treatments, which could lead to better medical care for patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trustees of Indiana University NIH-funded |
| Lab location | 1 site (Bloomington, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $310,278 |
| NIH project number | 5R21EB034938-02 |
| Project ID | NIH-10877767 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that require advanced imaging techniques for better understanding of tissue dynamics, such as those undergoing treatment for cancer or other diseases affecting cellular function.
✕Less likely to help
Patients who do not have conditions requiring detailed cellular imaging or who are not undergoing treatment that involves drug delivery systems may not benefit from this research.
What this research studies
This research focuses on developing a new imaging system that combines two advanced techniques, optical coherence microscopy and confocal fluorescence microscopy, to observe how cells behave in their natural environment. By using genetically modified animals and fluorescent nanoparticles, the study aims to capture detailed images of cells and their surroundings, allowing for a better understanding of how tissues respond to injury and treatment over time. The goal is to enable faster and more accurate imaging that can track cell dynamics in real-time, which is crucial for biomedical research and drug delivery applications.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for monitoring cell behavior and tissue responses, enhancing the effectiveness of treatments and drug delivery systems.
How similar studies have gone: Other research has shown promise in using multimodal imaging techniques for cellular observation, indicating that this approach could yield significant advancements in understanding tissue dynamics.
Where this research is happening
-
Trustees of Indiana University
Bloomington, United States Active
Researchers
- Principal investigator: Tankam, Patrice — Trustees of Indiana University
- Study coordinator: Tankam, Patrice
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.