Advanced imaging techniques for observing cell behavior in tissues
Concurrent volumetric imaging with multimodal optical systems
['FUNDING_R21'] · TRUSTEES OF INDIANA UNIVERSITY · NIH-10877767
This study is testing a new way to take detailed pictures of cells in their natural environment to help researchers understand how tissues heal and respond to treatments, which could lead to better medical care for patients.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TRUSTEES OF INDIANA UNIVERSITY (nih funded) |
| Locations | 1 site (BLOOMINGTON, UNITED STATES) |
| Trial ID | NIH-10877767 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new imaging system that combines two advanced techniques, optical coherence microscopy and confocal fluorescence microscopy, to observe how cells behave in their natural environment. By using genetically modified animals and fluorescent nanoparticles, the study aims to capture detailed images of cells and their surroundings, allowing for a better understanding of how tissues respond to injury and treatment over time. The goal is to enable faster and more accurate imaging that can track cell dynamics in real-time, which is crucial for biomedical research and drug delivery applications.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that require advanced imaging techniques for better understanding of tissue dynamics, such as those undergoing treatment for cancer or other diseases affecting cellular function.
Not a fit: Patients who do not have conditions requiring detailed cellular imaging or who are not undergoing treatment that involves drug delivery systems may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for monitoring cell behavior and tissue responses, enhancing the effectiveness of treatments and drug delivery systems.
How similar studies have performed: Other research has shown promise in using multimodal imaging techniques for cellular observation, indicating that this approach could yield significant advancements in understanding tissue dynamics.
Where this research is happening
BLOOMINGTON, UNITED STATES
- TRUSTEES OF INDIANA UNIVERSITY — BLOOMINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TANKAM, PATRICE — TRUSTEES OF INDIANA UNIVERSITY
- Study coordinator: TANKAM, PATRICE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.