Advanced imaging technique for analyzing biological tissues
Official title: Video Rate Photothermal Infrared Spectroscopy (VR-PTIR)
Funded at Photothermal Spectroscopy Corp. · NIH-10919106 · Data updated 2026-11-12
This study is testing a new imaging technique that helps doctors see and understand the tiny details in brain tissues affected by conditions like Alzheimer's disease much faster and clearer, which could lead to better diagnoses and treatments for patients.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Photothermal Spectroscopy Corp. NIH-funded |
| Lab location | 1 site (Santa Barbara, United States) |
| Project start | July 4, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $967,628 |
| NIH project number | 1R44GM154516-01 |
| Project ID | NIH-10919106 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or other neurodegenerative disorders.
✕Less likely to help
Patients with conditions unrelated to neurodegenerative diseases or those not requiring advanced imaging techniques may not benefit from this research.
What this research studies
This research focuses on developing a new imaging and spectroscopy technique called Video Rate Photothermal Infrared (VR-PTIR) that significantly improves the speed and resolution of infrared analysis of biological tissues. By achieving 10-30 times better spatial resolution and operating up to 1000 times faster than existing methods, this technology aims to enhance the understanding of molecular bonds in tissues affected by conditions like Alzheimer's disease and other neurodegenerative disorders. Patients may benefit from improved diagnostic capabilities and better-targeted treatments as a result of this advanced imaging technique.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatment options for patients with neurodegenerative diseases.
How similar studies have gone: Other research in the field of photothermal infrared spectroscopy has shown promise, indicating that this approach could lead to significant advancements in biomedical applications.
Where this research is happening
-
Photothermal Spectroscopy Corp.
Santa Barbara, United States Active
Researchers
- Principal investigator: Prater, Craig — Photothermal Spectroscopy Corp.
- Study coordinator: Prater, Craig
Related research
Other NIH-funded projects on the same topics.
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-
High-Speed, Automated Analysis of Tiny Microplastics
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-
Advanced Imaging for Alzheimer's Disease Research
This project is creating a new, super-fast microscope to get a much clearer look at tiny details in tissues, especially for conditions like Alzheimer's disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.