Advanced imaging system for drug discovery and biomarker analysis
Official title: Waters Desorption Electrospray (DESI) XS TQ Absolute imaging mass spectrometry system
Funded at University of Texas Med Br Galveston · NIH-11102859 · Data updated 2026-11-12
This study is all about using a new advanced imaging system to help scientists better understand how drugs work in the body, which can lead to discovering new treatments for diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Med Br Galveston NIH-funded |
| Lab location | 1 site (Galveston, United States) |
| Project start | May 1, 2025 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $593,598 |
| NIH project number | 1S10OD038289-01 |
| Project ID | NIH-11102859 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with conditions that are being targeted for new drug development and biomarker discovery.
✕Less likely to help
Patients with conditions that are not being studied or targeted by the drug discovery efforts may not receive any benefit from this research.
What this research studies
This research focuses on acquiring a state-of-the-art mass spectrometry imaging system to enhance drug discovery and development processes. By utilizing the DESI XS Xevo TQ Absolute mass spectrometer, researchers will create detailed 2-dimensional maps of drugs, metabolites, and disease biomarkers within biological tissues. This technology aims to improve the identification of druggable targets and provide insights into the absorption, distribution, metabolism, and excretion of drug candidates. The project will also address current limitations in mass spectrometry imaging access and capabilities for researchers.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective drugs and personalized treatment options for various diseases.
How similar studies have gone: Previous research utilizing mass spectrometry imaging has shown promising results in drug discovery and biomarker identification, indicating that this approach is both viable and beneficial.
Where this research is happening
-
University of Texas Med Br Galveston
Galveston, United States Active
Researchers
- Principal investigator: Prideaux, Brendan — University of Texas Med Br Galveston
- Study coordinator: Prideaux, Brendan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.