Advanced brain imaging techniques for Alzheimer's and related dementias

NAPS2 Neuroimaging Core

['FUNDING_OTHER'] · WASHINGTON UNIVERSITY · NIH-10866380

This study is looking at how brain changes in people with REM Sleep Behavior Disorder might help us understand Alzheimer's and similar conditions better, and it's for individuals with RBD who want to contribute to improving diagnosis and treatment.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorWASHINGTON UNIVERSITY (nih funded)
Locations1 site (SAINT LOUIS, UNITED STATES)
Trial IDNIH-10866380 on ClinicalTrials.gov

What this research studies

This research focuses on utilizing cutting-edge neuroimaging methods to study Alzheimer's disease and related dementias. The Neuroimaging Core will collect and analyze brain imaging data from over 300 participants with REM Sleep Behavior Disorder (RBD) at two different time points. By employing innovative imaging techniques, the project aims to enhance our understanding of neurodegenerative diseases and improve diagnostic capabilities. Participants will undergo advanced MRI and DaTscan imaging to gather comprehensive data on brain structure and function.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with REM Sleep Behavior Disorder and those at risk for Alzheimer's disease.

Not a fit: Patients with other types of dementia not related to Alzheimer's or REM Sleep Behavior Disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for patients with Alzheimer's and related dementias.

How similar studies have performed: Previous research has shown promise in using advanced neuroimaging techniques for studying neurodegenerative diseases, indicating potential for success in this approach.

Where this research is happening

SAINT LOUIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.