Advanced Brain Imaging Analysis for Multiple Sclerosis
Statistical Methods for Multilevel Multivariate Functional Studies
['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-11124847
This project creates new computer tools to better understand how Multiple Sclerosis affects the brain using advanced imaging scans.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11124847 on ClinicalTrials.gov |
What this research studies
We are developing advanced statistical methods to analyze complex brain imaging data from people with Multiple Sclerosis. This involves looking at detailed changes in brain white matter using Diffusion Tensor Imaging (DTI) and tracking changes in MS lesions with Magnetic Resonance Imaging (MRI) over time. Our goal is to create more accurate ways to interpret these scans, which could help us better understand the severity and progression of MS. These new tools will help researchers find better markers of the disease.
Who could benefit from this research
Good fit: Patients with Multiple Sclerosis who have undergone or will undergo advanced brain imaging may indirectly benefit from the improved analysis of their data.
Not a fit: Individuals without Multiple Sclerosis or those not involved in studies utilizing advanced brain imaging techniques would not directly benefit from this specific methods development.
Why it matters
Potential benefit: If successful, this work could lead to more precise ways to track Multiple Sclerosis progression and identify new biological markers, potentially guiding future treatment decisions.
How similar studies have performed: This project proposes novel biostatistical methods to address emerging data structures in neuroimaging, building upon existing imaging techniques but offering new analytical approaches.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CRAINICEANU, CIPRIAN M — JOHNS HOPKINS UNIVERSITY
- Study coordinator: CRAINICEANU, CIPRIAN M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease