Advanced Bioreactors for Growing Tissues
TR&D-3: Bio-instructive Bioreactors
This project is creating advanced systems to grow and mature personalized body tissues outside the body.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11123264 on NIH RePORTER |
What this research studies
We are developing new bioreactor systems that can grow and mature human tissues in a controlled environment. These systems will be able to measure how well the cells and tissues are developing without disturbing them. The goal is to create a closed system that can provide the right biological and mechanical signals to help tissues grow properly. This technology is especially important for creating personalized tissues, where only a single unit might be available.
Who could benefit from this research
Good fit: This foundational work does not directly involve patients, but future applications could benefit individuals needing tissue regeneration or replacement.
Not a fit: Patients not in need of tissue regeneration or replacement would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this technology could improve the quality and reliability of lab-grown tissues for transplantation or other medical uses.
How similar studies have performed: While bioreactors exist, the integration of advanced non-invasive sensing and feedback control for bio-instructive tissue maturation is a novel and developing area.
Where this research is happening
Cleveland, United States
- Case Western Reserve University — Cleveland, United States (Active)
Researchers
- Principal investigator: Baskaran, Harihara — Case Western Reserve University
- Study coordinator: Baskaran, Harihara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.